Very interesting article! This is from Medical Student Research Paper. The review article is talking about Alzheimer’s Disease (AD) how is the most common cause of irreversible dementia, accounting for up to 70% of all dementia cases in the United States. The author also point out other types of primary dementia include: vascular dementia, dementia associated with Parkinson’s disease, dementia with Lewy bodies, and frontotemporal dementia. The review emphasizes on dementia been a serious loss of mental abilities such as thinking, remembering, reasoning, and communicating. As dementia advances, these losses make it difficult to perform activities of daily living, such as driving, cooking, shopping, housekeeping, and eliminating. Social skills may be affected also. The author makes it clear that dementia is not a normal part of aging.
According to the review article “Epidemiology of AD”, states that AD is a critical health issue around the world, which is expected by 2030 to be affected by 65 millions of people and 115 million by 2050. The majority of victims are aged 65 and older. As people age, it is natural for them to experience a mild degree of memory loss. However, some cases can be much more severe, and can have a variety of causes. When loss of memory and other mental functions becomes more severe, the condition is known as dementia. AD is also a progressive neurodegenerative brain disorder.
In conclusion, this article is making it clear on how biomarkers are needed to identify high-risk patients for early treatment as well as for monitoring disease progression and response to treatment. Biomarker is good for early detection of AD, since Alois Alzheimer describe the first case of AD pre-dementia stages of AD, such as MCI, and the early detection of AD. I believe our knowledge on dementia and AD and will catalyze for AD than exist today and the future as we move toward a ‘cure’ for AD in the 21st century.