Aplastic Anemia is where the bone marrow doesn’t produce enough new blood cells that can cause health problems such as arrhythmias, enlarged heart, heart failure, infections and severe bleeding. To diagnose the doctor can order blood tests and/or bone marrow biopsy, X ray, CT scan, ultrasound imaging test, do a family history and a physical exam. Treatments depend on the severity of aplastic anemia. Minor cases are blood transfusion and medications, the more severe would require blood transfusions.
Hypovolemia is what it is called when you lose twenty percent of your body fluid or blood from any type of severe wound or cut, internal bleeding, ectopic pregnancy, endometriosis, prolonged diarrhea excessive vomiting, or excessive sweating. This then makes it impossible for the heart to pump enough fluid to the rest of the body which leads to organ failure. Hypovolemia is diagnosed by physical exams to see if there are any visible signs of bleeding or fluid leakage, blood tests for electrolyte imbalance, kidney and liver functions, CT scans or ultrasounds, echocardiogram and electrocardiogram of the heart, endoscopy, heart catheterization, or urinary catheter. To treat hypovolemia doctors will need blood plasma, platelet, red blood cell transfusions, and intravenous crystalloids. Doctors can also administer dopamine, dobutamine, epinephrine, and norepinephrine to help with circulation.
Pernicious anemia is where the body doesn’t absorb enough vitamin B-12, causing the body to not make enough red blood cells. As always the doctor will take a family history, physical exam and blood test. Treatment is more vitamins b-12, the doctor will have you take a shot for a couple of weeks then prescribe b-12 as pills.
The difference between these three anemias is how and what the affect. With hypovolemia being about the amounts of fluid in the body, aplastic anemia has to do with the bone barrow and pernicious anemia is not enough vitamin b-12.